Effect of Dapagliflozin on Glycemic Variability in Patients with Type 2 Diabetes under Insulin Glargine Combined with Other Oral Hypoglycemic Drugs

Effect of Rhus Coriaria L on Glycemic Control and Insulin Resistance in Patients with Type 2 Diabetes Mellitus

Objective: There are association between oxidative stress and incidence of some chronic diseases, such as type 2 diabetes mellitus (T2DM). Food containing antioxidant compounds, such as some spices, are the natural ways to deal with oxidative stress. The purpose of this study was to determine the effect of sumac powder (Rhus coriaria L) on the glycemic profile in patients with T2DM. Materials ...

Factors Associated with Glycemic Variability in Patients with Type 2 Diabetes: Focus on Oral Hypoglycemic Agents and Cardiovascular Risk Factors

BACKGROUND The role of glycemic variability (GV) in development of cardiovascular diseases remains controversial, and factors that determine glucose fluctuation in patients with diabetes are unknown. We investigated relationships between GV indices, kinds of oral hypoglycemic agents (OHAs), and cardiovascular risk factors in patients with type 2 diabetes mellitus (T2DM). METHODS We analyzed 2...

Adherence to Hypoglycemic Medication among Insulin-Treated Patients with Type 2 Diabetes

Effects of insulin-oral hypoglycemic agents combined therapy in outpatients with type 2 diabetes.

To evaluate the efficacy of combined insulin-OHAs therapy in subjects with NIDDM who received treatment with OHAs and insulin alone, we selected 60 outpatients divided in two groups: Group A: 36 subjects treated with OHAs therapy that received insulin treatment for secondary failure; Group B: 24 subjects in which OHAs therapy was added to insulin regimen to avoid the effects of hyperinsulinizat...

Clinical study of treatment switching from premixed insulin to basal insulin combined with oral hypoglycemic drugs in patients with type 2 diabetes

AIM Premixed insulin regimens are commonly used for the treatment of patients with type-2 diabetes mellitus (T2DM). However, limited data are available regarding next-step therapy options in cases where premixed insulin fails to provide adequate glycemic control. This 20-week observational study of everyday clinical practice evaluated the efficacy, safety and treatment satisfaction of insulin g...